Estrogen alone in postmenopausal women and breast cancer detection by means of mammography and breast biopsy.

Publication Type:

Journal Article


Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 28, Issue 16, p.2690-7 (2010)


2010, Age Distribution, Aged, Area Under Curve, Biopsy, Needle, Breast Neoplasms, Center-Authored Paper, Estrogen Replacement Therapy, Estrogens, Conjugated (USP), Female, Follow-Up Studies, Humans, Hysterectomy, Immunohistochemistry, Incidence, Mammography, Middle Aged, Neoplasm Staging, Postmenopause, Probability, Public Health Sciences Division, Reference Values, Risk Assessment, ROC Curve, Survival Rate, Time Factors


As the influence of estrogen alone on breast cancer detection is not established, we examined this issue in the Women's Health Initiative trial, which randomly assigned 10,739 postmenopausal women with prior hysterectomy to conjugated equine estrogen (CEE; 0.625 mg/d) or placebo.