Efficacy of hyperthermic isolated limb perfusion for extremity-confined recurrent melanoma.

Publication Type:

Journal Article


Annals of surgical oncology, Volume 5, Issue 4, p.376-83 (1998)


Antineoplastic Agents, Extremities, Female, Humans, Hyperthermia, Induced, Male, MELANOMA, Middle Aged, Multivariate Analysis, Neoplasm Recurrence, Local, Perfusion, Prospective Studies, Survival Analysis


Recurrent melanoma of the extremity has been treated by local excision, systemic chemotherapy, amputation, or a combination of these approaches. Hyperthermic isolated limb perfusion (HILP) provides a method of limb preservation through isolation, allowing the administration of chemotherapy in higher doses than is possible through systemic treatment.