Effects of estrogen with and without progestin and obesity on symptomatic gastroesophageal reflux.

Publication Type:

Journal Article


Gastroenterology, Volume 135, Issue 1, p.72-81 (2008)


2008, Aged, Body Mass Index, Estrogen Replacement Therapy, Estrogens, Estrogens, Conjugated (USP), Female, Gastroesophageal Reflux, Humans, Hysterectomy, Incidence, Medroxyprogesterone Acetate, Middle Aged, Obesity, Public Health Sciences Division, RISK, Risk Factors, Waist-Hip Ratio


An association between female hormones and symptomatic gastroesophageal reflux disease (GERD) and may be modified by obesity is suggested but not proven. Factors affecting GERD progression, however, are largely unknown.