Effective treatment of acute promyelocytic leukemia with all-trans-retinoic acid, arsenic trioxide, and gemtuzumab ozogamicin.
Publication Type:
Journal ArticleSource:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 27, Issue 4, p.504-10 (2009)Keywords:
Adolescent, Adult, Aged, Aged, 80 and over, Aminoglycosides, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Arsenicals, Drug Administration Schedule, Female, Follow-Up Studies, Humans, Leukemia, Promyelocytic, Acute, Male, Middle Aged, Oxides, Polymerase Chain Reaction, Remission Induction, Survival Rate, Treatment Outcome, TretinoinAbstract:
We examined the outcome of patients with newly diagnosed acute promyelocytic leukemia (APL) treated with all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO) with or without gemtuzumab ozogamicin (GO) but without traditional cytotoxic chemotherapy.
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