Effect of finasteride on serum androstenedione and risk of prostate cancer within the prostate cancer prevention trial: differential effect on high- and low-grade disease.

Publication Type:

Journal Article

Source:

Urology, Volume 85, Issue 3, p.616-20 (2015)

Keywords:

Androstenedione, Case-Control Studies, Double-Blind Method, Finasteride, Humans, Male, Middle Aged, Neoplasm Grading, Prostatic Neoplasms, Risk Assessment

Abstract:

To evaluate the effect of finasteride on serum androst-4-ene-3,17-dione (androstenedione) and its association with prostate cancer risk among subjects who participated in the Prostate Cancer Prevention Trial.