The Early Detection Research Network's Specimen Reference Sets: Paving the Way for Rapid Evaluation of Potential Biomarkers.

Publication Type:

Journal Article

Source:

Clinical chemistry, Volume 59, Issue 1, p.68-74 (2013)

Keywords:

December 2012, Public Health Sciences Division, Vaccine and Infectious Disease Division

Abstract:

The mission of the National Cancer Institute's Early Detection Research Network (EDRN) is to identify and validate cancer biomarkers for clinical use. Since its inception, EDRN investigators have learned a great deal about the process of validating biomarkers for clinical use. Translational research requires a broad spectrum of research expertise, and coordinating collaborative activities can be challenging. The EDRN has developed a robust triage and validation system that serves the roles of both "facilitator" and "brake."