Diet intervention and cerebrospinal fluid biomarkers in amnestic mild cognitive impairment.

Publication Type:

Journal Article


Archives of neurology, Volume 68, Issue 6, p.743-52 (2011)


2011, Aged, Alzheimer Disease, Amnesia, Amyloid beta-Peptides, Biological Markers, Center-Authored Paper, Cognition Disorders, Dietary Carbohydrates, Dietary Fats, Unsaturated, Female, Food, Formulated, Humans, Male, Middle Aged, Peptide Fragments, Prevention Center Core Facility, Public Health Sciences Division, Severity of Illness Index, Shared Resources


To compare the effects of a 4-week high-saturated fat/high-glycemic index (HIGH) diet with a low-saturated fat/low-glycemic index (LOW) diet on insulin and lipid metabolism, cerebrospinal fluid (CSF) markers of Alzheimer disease, and cognition for healthy adults and adults with amnestic mild cognitive impairment (aMCI).