Diagnostic markers for early detection of ovarian cancer.

Publication Type:

Journal Article


Clinical cancer research : an official journal of the American Association for Cancer Research, Volume 14, Issue 4, p.1065-72 (2008)


2008, Adult, Aged, Aged, 80 and over, Area Under Curve, CA-125 Antigen, Cytokines, Early Diagnosis, Enzyme-Linked Immunosorbent Assay, False Positive Reactions, Female, Growth Differentiation Factor 15, Humans, Insulin-Like Growth Factor II, Leptin, Middle Aged, Osteopontin, Ovarian Neoplasms, Prolactin, Public Health Sciences Division, Sensitivity and Specificity, Tumor Markers, Biological


Early detection would significantly decrease the mortality rate of ovarian cancer. In this study, we characterize and validate the combination of six serum biomarkers that discriminate between disease-free and ovarian cancer patients with high efficiency.