Diagnostic markers for early detection of ovarian cancer.

Publication Type:

Journal Article

Source:

Clinical cancer research : an official journal of the American Association for Cancer Research, Volume 14, Issue 4, p.1065-72 (2008)

Keywords:

2008, Adult, Aged, Aged, 80 and over, Area Under Curve, CA-125 Antigen, Cytokines, Early Diagnosis, Enzyme-Linked Immunosorbent Assay, False Positive Reactions, Female, Growth Differentiation Factor 15, Humans, Insulin-Like Growth Factor II, Leptin, Middle Aged, Osteopontin, Ovarian Neoplasms, Prolactin, Public Health Sciences Division, Sensitivity and Specificity, Tumor Markers, Biological

Abstract:

Early detection would significantly decrease the mortality rate of ovarian cancer. In this study, we characterize and validate the combination of six serum biomarkers that discriminate between disease-free and ovarian cancer patients with high efficiency.