Daidzein-metabolizing phenotypes in relation to serum hormones and sex hormone binding globulin, and urinary estrogen metabolites in premenopausal women in the United States.

Publication Type:

Journal Article

Source:

Cancer causes & control : CCC, Volume 19, Issue 10, p.1085-93 (2008)

Keywords:

2008, Adult, Center-Authored Paper, Estrogens, Female, Gonadal Steroid Hormones, Humans, Isoflavones, Linear Models, PHENOTYPE, Premenopause, Public Health Sciences Division, Sex Hormone-Binding Globulin, Shared Resources, Specimen Processing Core Facility, United States

Abstract:

Blood and urine concentrations of hormones are implicated in the etiology of some cancers. Small studies have assessed relationships between production of the daidzein metabolites equol and O-desmethylangolensin (ODMA) and hormones, but findings are unclear. We evaluated relationships between daidzein-metabolizing phenotypes and follicular phase concentrations of estrogens, androgens, sex hormone binding globulin (SHBG), and urinary estrogen metabolites in premenopausal women.