Daidzein-metabolizing phenotypes in relation to serum hormones and sex hormone binding globulin, and urinary estrogen metabolites in premenopausal women in the United States.

Publication Type:

Journal Article


Cancer causes & control : CCC, Volume 19, Issue 10, p.1085-93 (2008)


2008, Adult, Center-Authored Paper, Estrogens, Female, Gonadal Steroid Hormones, Humans, Isoflavones, Linear Models, PHENOTYPE, Premenopause, Public Health Sciences Division, Sex Hormone-Binding Globulin, Shared Resources, Specimen Processing Core Facility, United States


Blood and urine concentrations of hormones are implicated in the etiology of some cancers. Small studies have assessed relationships between production of the daidzein metabolites equol and O-desmethylangolensin (ODMA) and hormones, but findings are unclear. We evaluated relationships between daidzein-metabolizing phenotypes and follicular phase concentrations of estrogens, androgens, sex hormone binding globulin (SHBG), and urinary estrogen metabolites in premenopausal women.