Current Use and Trends in Hematopoietic Cell Transplantation in the United States.

Publication Type:

Journal Article


Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation (2017)


Hematopoietic cell transplantation (HCT) is an established curative treatment for a number of malignant and non-malignant diseases involving the hematopoietic system and some solid tumors. In this report, we provide information about the number of HCT procedures performed in the United States (US) in 2015 and analyze trends and outcomes of HCT as reported to the Center for International Blood and Marrow Transplant Research(®) (CIBMTR(®)). We show that the numbers of HCT performed annually continue to increase, the indications for HCT, preferred donor sources and GVHD prophylaxis continue to evolve. We report on general overall survival by indication, disease status at transplant and by transplant type. This report demonstrates a current perspective on transplant activity in the US with focus on recent trends in alternative donors and contemporary transplant practices.