Cord blood transplantation for haematological malignancies: conditioning regimens, double cord transplant and infectious complications.

Publication Type:

Journal Article

Source:

British journal of haematology, Volume 147, Issue 2, p.207-16 (2009)

Keywords:

2009, Algorithms, Biologics Production Core Facility, Center-Authored Paper, Clinical Research Division, Cord Blood Stem Cell Transplantation, Donor Selection, Flow Cytometry Core Facility, Hematologic Neoplasms, Humans, Opportunistic Infections, Shared Resources, Transplantation Conditioning, Whole-Body Irradiation

Abstract:

Growing evidence supports the efficacy of cord blood transplantation (CBT) to treat patients with haematological malignancies, and the number of CBTs is rapidly increasing. Herein, we review considerations regarding conditioning regimens for CBT, the impact of double unit transplantation on CBT outcomes, and data regarding infectious complications following CBT.