Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk.

Publication Type:

Journal Article

Authors:

Kelemen, Linda E; Terry, Kathryn L; Goodman, Marc T; Webb, Penelope M; Bandera, Elisa V; McGuire, Valerie; Rossing, Mary Anne; Wang, Qinggang; Dicks, Ed; Tyrer, Jonathan P; Song, Honglin; Kupryjanczyk, Jolanta; Dansonka-Mieszkowska, Agnieszka; Plisiecka-Halasa, Joanna; Timorek, Agnieszka; Menon, Usha; Gentry-Maharaj, Aleksandra; Gayther, Simon A; Ramus, Susan J; Narod, Steven A; Risch, Harvey A; McLaughlin, John R; Siddiqui, Nadeem; Glasspool, Rosalind; Paul, James; Carty, Karen; Gronwald, Jacek; Lubiński, Jan; Jakubowska, Anna; Cybulski, Cezary; Kiemeney, Lambertus A; Massuger, Leon F A G; van Altena, Anne M; Aben, Katja K H; Olson, Sara H; Orlow, Irene; Cramer, Daniel W; Levine, Douglas A; Bisogna, Maria; Giles, Graham G; Southey, Melissa C; Bruinsma, Fiona; Kjaer, Susanne K; Høgdall, Estrid; Jensen, Allan; Høgdall, Claus K; Lundvall, Lene; Engelholm, Svend-Aage; Heitz, Florian; du Bois, Andreas; Harter, Philipp; Schwaab, Ira; Butzow, Ralf; Nevanlinna, Heli; Pelttari, Liisa M; Leminen, Arto; Thompson, Pamela J; Lurie, Galina; Wilkens, Lynne R; Lambrechts, Diether; Van Nieuwenhuysen, Els; Lambrechts, Sandrina; Vergote, Ignace; Beesley, Jonathan; Fasching, Peter A; Beckmann, Matthias W; Hein, Alexander; Ekici, Arif B; Doherty, Jennifer A; Wu, Anna H; Pearce, Celeste L; Pike, Malcolm C; Stram, Daniel; Chang-Claude, Jenny; Rudolph, Anja; Dörk, Thilo; Dürst, Matthias; Hillemanns, Peter; Runnebaum, Ingo B; Bogdanova, Natalia; Antonenkova, Natalia; Odunsi, Kunle; Edwards, Robert P; Kelley, Joseph L; Modugno, Francesmary; Ness, Roberta B; Karlan, Beth Y; Walsh, Christine; Lester, Jenny; Orsulic, Sandra; Fridley, Brooke L; Vierkant, Robert A; Cunningham, Julie M; Wu, Xifeng; Lu, Karen; Liang, Dong; Hildebrandt, Michelle A T; Weber, Rachel Palmieri; Iversen, Edwin S; Tworoger, Shelley S; Poole, Elizabeth M; Salvesen, Helga B; Krakstad, Camilla; Bjorge, Line; Tangen, Ingvild L; Pejovic, Tanja; Bean, Yukie; Kellar, Melissa; Wentzensen, Nicolas; Brinton, Louise A; Lissowska, Jolanta; Garcia-Closas, Montserrat; Campbell, Ian G; Eccles, Diana; Whittemore, Alice S; Sieh, Weiva; Rothstein, Joseph H; Anton-Culver, Hoda; Ziogas, Argyrios; Phelan, Catherine M; Moysich, Kirsten B; Goode, Ellen L; Schildkraut, Joellen M; Berchuck, Andrew; Pharoah, Paul D P; Sellers, Thomas A; Brooks-Wilson, Angela; Cook, Linda S; Le, Nhu D

Source:

Molecular nutrition & food research (2014)

Keywords:

2014, August 2014, Public Health Sciences Division

Abstract:

We reevaluated previously reported associations between variants in pathways of one-carbon (1-C) (folate) transfer genes and ovarian carcinoma (OC) risk, and in related pathways of purine and pyrimidine metabolism, and assessed interactions with folate intake.