Comparison of endogenous and overexpressed MyoD shows enhanced binding of physiologically bound sites.

Publication Type:

Journal Article

Authors:

Yao, Zizhen; Fong, Abraham P; Cao, Yi; Ruzzo, Walter L; Gentleman, Robert C; Tapscott, Stephen J

Source:

Skeletal muscle, Volume 3, Issue 1, p.8 (2013)

Keywords:

2013, Clinical Research Division, Human Biology Division, May 2013

Abstract:

Transcription factor overexpression is common in biological experiments and transcription factor amplification is associated with many cancers, yet few studies have directly compared the DNA-binding profiles of endogenous versus overexpressed transcription factors.