Analysis of metabolic syndrome components in >15 000 african americans identifies pleiotropic variants: results from the population architecture using genomics and epidemiology study.

Publication Type:

Journal Article


Circulation. Cardiovascular genetics (2014)


2014, August 2014, Center-Authored Paper, Public Health Sciences Division, Scientific Imaging Core Facility, Specimen Processing Core Facility


-Metabolic syndrome (MetS) refers to the clustering of cardio-metabolic risk factors including dyslipidemia, central adiposity, hypertension and hyperglycemia in individuals. Identification of pleiotropic genetic factors associated with MetS traits may shed light on key pathways or mediators underlying MetS.