A cohort study of developmental polychlorinated biphenyl (PCB) exposure in relation to post-vaccination antibody response at 6-months of age.

Publication Type:

Journal Article


Environmental research, Volume 110, Issue 4, p.388-95 (2010)


2010, Adolescent, Adult, Antibodies, Bacterial, Bacterial Vaccines, Center-Authored Paper, Cohort Studies, Diphtheria Toxoid, Environmental Exposure, Female, Fetal Blood, Growth and Development, Haemophilus influenzae type b, Haemophilus Vaccines, Humans, Immunoglobulin G, Infant, Male, Maternal Exposure, Polychlorinated Biphenyls, PREGNANCY, Public Health Sciences Division, Tetanus Toxoid, Young Adult


Extensive experimental data in animals indicate that exposure to polychlorinated biphenyls (PCBs) during pregnancy leads to changes in offspring immune function during the postnatal period. Whether developmental PCB exposure influences immunologic development in humans has received little study.