Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet.

Publication Type:

Journal Article


Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 27, Issue 35, p.6041-51 (2009)


2009, Antineoplastic Agents, Clinical Research Division, Drug Administration Schedule, Drug Monitoring, Europe, Gene Expression Regulation, Leukemic, hematopoietic stem cell transplantation, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Piperazines, Protein Kinase Inhibitors, Pyrimidines, Thiazoles, Time Factors, Transplantation, Homologous, Treatment Failure, Treatment Outcome


To review and update the European LeukemiaNet (ELN) recommendations for the management of chronic myeloid leukemia with imatinib and second-generation tyrosine kinase inhibitors (TKIs), including monitoring, response definition, and first- and second-line therapy.