Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet.

Publication Type:

Journal Article

Source:

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 27, Issue 35, p.6041-51 (2009)

Keywords:

2009, Antineoplastic Agents, Clinical Research Division, Drug Administration Schedule, Drug Monitoring, Europe, Gene Expression Regulation, Leukemic, hematopoietic stem cell transplantation, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Piperazines, Protein Kinase Inhibitors, Pyrimidines, Thiazoles, Time Factors, Transplantation, Homologous, Treatment Failure, Treatment Outcome

Abstract:

To review and update the European LeukemiaNet (ELN) recommendations for the management of chronic myeloid leukemia with imatinib and second-generation tyrosine kinase inhibitors (TKIs), including monitoring, response definition, and first- and second-line therapy.