A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk.

Publication Type:

Journal Article


Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Volume 19, Issue 7, p.1812-21 (2010)


2010, Case-Control Studies, Center-Authored Paper, Colorectal Neoplasms, Dietary Supplements, Epidemiology Core Facility, Female, folic acid, Genetic Predisposition to Disease, Genotype, Humans, Male, Microsatellite Instability, Middle Aged, Polymorphism, Single Nucleotide, Public Health Sciences Division, Shared Resources, Specimen Processing Core Facility, United States, Vitamin B 12


Folate-associated one-carbon metabolism (FOCM) may play an important role in colorectal carcinogenesis. Variation in FOCM genes may explain some of the underlying risk of colorectal cancer.