Calcium/vitamin D supplementation and coronary artery calcification in the Women's Health Initiative.

Publication Type:

Journal Article


Menopause (New York, N.Y.), Volume 17, Issue 4, p.683-91 (2010)


2010, Bone Density Conservation Agents, Calcinosis, Calcium Carbonate, Center-Authored Paper, Cholecalciferol, Coronary Angiography, Coronary Artery Disease, Double-Blind Method, Female, Humans, Middle Aged, Postmenopause, Public Health Sciences Division, Tomography, X-Ray Computed


Coronary artery calcified plaque is a marker for atheromatous plaque burden and predicts future risk of cardiovascular events. The relationship between calcium plus vitamin D (calcium/D) supplementation and coronary artery calcium (CAC) has not been previously assessed in a randomized trial setting. We compared CAC scores after trial completion between women randomized to calcium/vitamin D supplementation and women randomized to placebo.