Calcium plus vitamin D supplementation and the risk of breast cancer.

Publication Type:

Journal Article


Journal of the National Cancer Institute, Volume 100, Issue 22, p.1581-91 (2008)


2008, Aged, Body Mass Index, Breast Neoplasms, Calcium Compounds, Carcinoma, Ductal, Breast, Case-Control Studies, Dietary Supplements, Double-Blind Method, Drug Administration Schedule, Female, Humans, Incidence, Kaplan-Meier Estimate, Mammography, Middle Aged, Odds Ratio, Patient Selection, Postmenopause, Proportional Hazards Models, Public Health Sciences Division, Risk Assessment, Risk Factors, United States, Vitamin D


Although some observational studies have associated higher calcium intake and especially higher vitamin D intake and 25-hydroxyvitamin D levels with lower breast cancer risk, no randomized trial has evaluated these relationships.