Body size, IGF and growth hormone polymorphisms, and colorectal adenomas and hyperplastic polyps.

Publication Type:

Journal Article

Source:

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, Volume 20, Issue 4, p.305-9 (2010)

Keywords:

2010, Adenoma, Body Size, Center-Authored Paper, Collaborative Data Services Core Facility, Colon, Colonic Polyps, Colorectal Neoplasms, Genetic Predisposition to Disease, Human Growth Hormone, Humans, HYPERPLASIA, Insulin-Like Growth Factor I, Polymorphism, Genetic, Public Health Sciences Division, Shared Resources, Specimen Processing Core Facility

Abstract:

We examined the risk of colorectal polyps in relation to body size factors and candidate polymorphisms in selected genes of insulin-like growth factor (IGF1) (rs5742612), IGF1 receptor (IGF1R) (rs2229765), IGF binding protein 3 (IGFBP3) (rs2854746) and growth hormone (GH1) (rs2665802).