Baseline serum estradiol and fracture reduction during treatment with hormone therapy: the Women's Health Initiative randomized trial.

Publication Type:

Journal Article


Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, Volume 21, Issue 1, p.167-77 (2010)


2010, Aged, Biological Markers, Center-Authored Paper, Epidemiologic Methods, estradiol, Estrogen Replacement Therapy, Female, Hip Fractures, Humans, Hysterectomy, Middle Aged, Osteoporosis, Postmenopausal, Osteoporotic Fractures, Public Health Sciences Division, Sex Hormone-Binding Globulin, Treatment Outcome


The purpose of the study was to test the hypothesis that the reduction in fractures with hormone therapy (HT) is greater in women with lower estradiol levels.