The Aurora B Kinase Promotes Inner and Outer Kinetochore Interactions in Budding Yeast.

Publication Type:

Journal Article


Genetics, Volume 194, Issue 3, p.785-9 (2013)


2013, Basic Sciences Division, Center-Authored Paper, Genomics Core Facility, May 2013, Scientific Imaging Core Facility


The kinetochore is the macromolecular protein complex that mediates chromosome segregation. The Dsn1 component is crucial for kinetochore assembly and is phosphorylated by the Aurora B kinase. We found that Aurora B phosphorylation of Dsn1 promotes the interaction between outer and inner kinetochore proteins in budding yeast.