Associations of insulin resistance and adiponectin with mortality in women with breast cancer.

Publication Type:

Journal Article


Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 29, Issue 1, p.32-9 (2011)


2011, Adiponectin, Adult, Aged, Aged, 80 and over, Blood Glucose, Body Mass Index, Body Weight, Breast Neoplasms, Center-Authored Paper, Cohort Studies, Female, Humans, Hyperinsulinism, Insulin, Insulin Resistance, Middle Aged, Obesity, Prevention Center Core Facility, Prospective Studies, Public Health Sciences Division, Risk Factors, Shared Resources


Overweight or obese breast cancer patients have a worse prognosis compared with normal-weight patients. This may be attributed to hyperinsulinemia and dysregulation of adipokine levels associated with overweight and obesity. Here, we evaluate whether low levels of adiponectin and a greater level of insulin resistance are associated with breast cancer mortality and all-cause mortality.