Associations of insulin resistance and adiponectin with mortality in women with breast cancer.

Publication Type:

Journal Article

Source:

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Volume 29, Issue 1, p.32-9 (2011)

Keywords:

2011, Adiponectin, Adult, Aged, Aged, 80 and over, Blood Glucose, Body Mass Index, Body Weight, Breast Neoplasms, Center-Authored Paper, Cohort Studies, Female, Humans, Hyperinsulinism, Insulin, Insulin Resistance, Middle Aged, Obesity, Prevention Center Core Facility, Prospective Studies, Public Health Sciences Division, Risk Factors, Shared Resources

Abstract:

Overweight or obese breast cancer patients have a worse prognosis compared with normal-weight patients. This may be attributed to hyperinsulinemia and dysregulation of adipokine levels associated with overweight and obesity. Here, we evaluate whether low levels of adiponectin and a greater level of insulin resistance are associated with breast cancer mortality and all-cause mortality.