Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status.

Publication Type:

Journal Article

Source:

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Volume 18, Issue 10, p.2745-50 (2009)

Keywords:

2009, Adult, Alcohol Drinking, Center-Authored Paper, Colorectal Neoplasms, DNA Mismatch Repair, Epidemiology Core Facility, Female, Humans, Male, Microsatellite Instability, Middle Aged, Public Health Sciences Division, Registries, Risk Factors, Shared Resources, Smoking, Specimen Processing Core Facility, Young Adult

Abstract:

Both smoking and alcohol consumption have been associated with modestly increased risks of colorectal cancer (CRC). Reports have suggested that these associations may differ by tumor molecular subtype, with stronger associations for microsatellite unstable (MSI-H) tumors.