Altered biomarkers of mucosal immunity and reduced vaginal lactobacillus concentrations in sexually active female adolescents.

Publication Type:

Journal Article


PloS one, Volume 7, Issue 7, p.e40415 (2012)


2012, August 2012, Basic Sciences Division, Center-Authored Paper, Genomics Core Facility, Shared Resources, Vaccine and Infectious Disease Division


Genital secretions collected from adult women exhibit in vitro activity against herpes simplex virus (HSV) and Escherichia coli (E. coli), but prior studies have not investigated this endogenous antimicrobial activity or its mediators in adolescent females.