Kenneth J. Kopecky

Appointments and Affiliations

Fred Hutchinson Cancer Research Center
Public Health Sciences
Emeritus Member
University of Washington
School of Public Health and Community Medicine
Affiliate Professor
Professional Headshot of Kenneth K. Kopecky

Mailing Address

Southwest Oncology Group
1100 Fairview Avenue N.
P.O. Box 19024
Seattle, Washington 98109-1024
United States


Phone: (206) 667-4623


Ph.D., Oregon State University, 1977.
M.S., Oregon State University, 1975.

Research Interests

Southwest Oncology Group Statistical Center (Leukemia And Leukemia Biology) And Radiation Epidemiology.

The Leukemia Committee and Leukemia Biology Program of the Southwest Oncology Group conduct a variety of studies concerning adult leukemias. These include clinical trials of new and promising treatments for the various kinds of leukemia, as well as laboratory studies to elucidate the biological mechanisms underlying the pathogenesis and prognosis of these diseases. The investigators at the Southwest Oncology Group Statistical Center collaborate in the design, conduct, analysis and reporting of these studies.

A continuing major focus of the Southwest Oncology Group's leukemia research is the problem of multidrug resistance. Patients whose leukemia is resistant to remission induction therapy have a very poor prognosis. Recent and ongoing studies have shown that such resistance is a complex phenomenon, possibly involving multiple mechanisms, some of which protect leukemic cells from cytotoxic agents,and others of which may interfere with that protection. The Group's studies are intended to elucidate these mechanisms, with the ultimate goal of finding ways to overcome multidrug resistance.

Radiation epidemiology is the study of how risks of diseases such as certain types of cancer are affected when people are exposed to radiation. The Hanford Thyroid Disease Study investigated whether thyroid disease, including thyroid cancer, has been increased among persons exposed to radioactive iodine released from the Hanford Nuclear Site in south-central Washington State during the 1940s and 1950s. Scientists from the Fred Hutchinson Cancer Research Center are also engaged with Russian colleagues in a multinational project (the International Consortium for Research on the Health Effects of Radiation) to investigate the radiation doses and health consequences in areas of Russia contaminated by fallout from the Chernobyl accident in April 1986. This project includes a case-control studies of thyroid cancer and leukemia among persons who were exposed to radiation from the accident.


Recent Publications

Othus M, Appelbaum FR, Petersdorf SH, Kopecky KJ, Slovak M, Nevill T, Brandwein J, Larson RA, Stiff PJ, Walter RB et al..  2015.  Fate of patients with newly diagnosed acute myeloid leukemia who fail primary induction therapy.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 21(3):559-64. Abstract
McDougall JA, Sakata R, Sugiyama H, Grant E, Davis S, Nishi N, Soda M, Shimizu Y, Tatsukawa Y, Kasagi F et al..  2010.  Timing of menarche and first birth in relation to risk of breast cancer in A-bomb survivors.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 19(7):1746-54. Abstract

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