Ruth Etzioni

Appointments and Affiliations

Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Biostatistics Program
Translational & Outcomes Research Group
Full Member, Appointed: 2002
University of Washington
Affilitate Professor, Appointed: 1997
Professional Headshot of Ruth  Etzioni

Mailing Address

Fred Hutchinson Cancer Research Center
1100 Fairview Avenue North
P.O. Box 19024
Seattle, Washington 98109-1024
United States


Phone: (206) 667-6561
Fax: (206) 667-7264


Ph.D., Carnegie Mellon University, Statistics, 1990.
M.S., Carnegie Mellon University, Statistics, 1987.
B.S., University of Cape Town, Statistics, 1985.

Research Interests

Cancer screening
Methods for evaluating diagnostic tests
Modeling and outcomes research in prostate cancer
Modeling impact of PSA screening and other interventions on prostate cancer incidence and mortality
Costs and benefits of prostate cancer screening
Trends in prostate cancer screening and related behaviors

Dr. Ruth (Douglas) Etzioni is a Full Member in Biostatistics of the Division of Public Health Sciences at the Fred Hutchinson Cancer Research Center. Her work focuses on the development and implementation of statistical methods for prostate cancer studies. In the past, she has worked on assessing the efficacy of PSA screening from population studies, estimating the frequency of overdiagnosis associated with PSA, evaluating novel prostate cancer biomarkers, and tracking patterns and outcomes of prostate cancer care. Her work in prostate cancer surveillance is conducted as part of the Cancer Intervention and Surveillance Modeling Network (CISNET).

As leader of the biostatistics core for the Northwest Prostate Cancer SPORE, Dr. Etzioni has developed methods for analyzing immunohistochemical studies, and combining results from microarray experiments, while working with SPORE investigators to select the most appropriate design and analysis approaches for a broad array of studies. She is an affiliate investigator on the Data Management Coordination Center for the Early Detection Research Network (EDRN) and continues to work with EDRN statisticians on methods for biomarker development. In addition to these projects, her current interests include modeling the development of resistance to androgen ablation therapy.


American Statistical Association
Institute of Mathematical Statistics
International Biometric Society
Society for Medical Decision Making

Honors and Awards

2016, American Statistical Association Fellow


  • NIH/NCI: Pacific Northwest Prostate Cancer SPORE, Core C: Biostatistics Core (PI), $88,234 (direct), May 1, 2002 to 2012.
  • NIH/NCI: Outcomes Based Guidelines Development for Prostate Cancer Screening and Treatment, $172,221, 2008 to 2012.
  • NIH/NCI: Primary Prevention versus Screening for Prostate Cancer (PI), $178,000 (annual dir, 2003 to 2009.
  • NCI: Modeling US prostate cancer trends: PSA, treatment and risk: Cancer Intervention Surveillance Modeling Network (PI), $153,065 (annual dir, 2000 to 2010.


Recent Publications

Lange JM, Trock BJ, Gulati R, Etzioni R.  2017.  A Framework for Treatment Decision Making at Prostate Cancer Recurrence.. Medical decision making : an international journal of the Society for Medical Decision Making. :272989X17711913. Abstract
Mariotto AB, Etzioni R, Hurlbert M, Penberthy L, Mayer M.  2017.  Estimation of the Number of Women Living with Metastatic Breast Cancer in the United States.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 26(6):809-815. Abstract
Gulati R, Cheng HH, Lange PH, Nelson PS, Etzioni R.  2016.  Screening men at increased risk for prostate cancer diagnosis: Model estimates of benefits and harms.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Abstract

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