Pricing Changes in Experimental Histopathology

Related Core Facilities:

Friday 06/12/2015

We have not had a price adjustment since 2010. Therefore, Experimental Histopathology has undergone a major restructuring of our pricing. We have made some significant changes in how we charge for services such as embedding samples in OCT, cutting frozen sections, staining for immunohistochemistry and immunofluorescence, and how we charge for antibody work-ups or optimization (details below). We have also added several new services based on the needs of users. All of this was done based on user feedback to make planning and budgeting easier, to reflect the increasing cost of reagents, and to decrease the subsidies provided by the Hutch.

OCT embedded tissue:
We will no longer have a separate charge for embedding the first tissue in OCT and then another charge for additional blocks. We will have a flat charge to embed 1 to 10 tissues in OCT. In addition, we will no longer have a separate charge for the first section cut from an OCT block. We will have one price per cut slide; similar to paraffin block sectioning.

Cytology samples:
We now have a charge for preparing cells for various staining assays. First, we have a flat rate to prepare 1 to 4 cytospin slides from one sample. In addition, we now have a charge to prepare a histogel cell pellet for paraffin processing.

Instead of charging for extra slides to account for positive and isotype controls per case, we have rolled those charges into the price per slide for all of the IHC and IF charges. For example, previously if you submitted 12 slides for Ki67 staining, you would have been charged for 15 slides – your 12 slides plus 1 positive control, 1 isotype control from the positive control tissue, and 1 isotype control for a tissue in your case. Now you will only be charged for 12 slides.

You will now be charged a flat rate of $3 per slide when Experimental Histopathology provides the antibody. You will no longer be charges for antibodies under “Supplies”.

We have eliminated the extra charge for “Amplified” IHC and IF. We rarely use the technique for single IHC and IF procedures and almost always use these techniques in dual and triple IF. The new charges reflect the use of the amplification reagents in the cost of dual and triple IF only.

Antibody Work-Ups:
Previously, we charged per slide for antibody work-ups. This made it very difficult for investigators to plan a budget. We have prepared a menu with accompanying charges for any optimization from a single antibody visualized with DAB up to 3 antibodies used in a triple IF stain. Please see this document for the full description of services.

The cost to maintain the software to run the Aperio system is included in the cost per slide for brightfield scanning on the Aperio XT and the price per hour for fluorescence scanning on the Aperio FL. However, we now need to maintain the licenses and maintenance of Definiens software so we will be charging a small per hour fee starting in June 2015 to cover those costs.

Experimental Histopathology is committed to providing the highest quality samples while maintaining costs. Please let us know if we can help you with your research or if there are new technologies you would like us to add to our services. If you have any questions, please feel free to contact Julie Randolph-Habecker at

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Shared Resources are core facilities that provide services and access to specialized equipment for research activities.

Rajesh K. Uthamanthil, DVM, PhD, DACLAM

Associate Vice President, Shared Resources