New Digital Ultrasound System - Vevo 2100

Related Core Facilities:

Friday 09/21/2012

Comparative Medicine has a new Vevo® 2100, - a powerful digital ultrasound system for rodents with a resolution of 30 microns. The Vevo® 2100 is the first high-frequency, high-resolution digital imaging platform with linear array technology and Color Doppler Mode.

This system expands the functionality, flexibility and image quality of the older Vevo 770 system, operating at frequencies never before achieved with solid-state array transducers.

The MicroScan transducers provide increased frame rates, superb contrast, unrivaled resolution and a wider field of view. It is easy to use, non-invasive & fast, providing extremely high throughput when needed. 

Potential uses include the following examples.

Cancer Research

  • Detection and accurate sizing of small pre-palpable tumors in 2D and 3D
  • Quantification of perfusion using microbubble contrast agents
  • Assessment of endothelial cell biomarker expression with antibody-targeted microbubbles
  • Targeted, minimally invasive cancer cell delivery for xenograft models

Developmental Biology

  • Ultrasound-guided injections of cells, genetic material, drugs, and retroviruses
  • Visualize & quantify rodent embryonic development
  • Non-invasive monitoring of development to assess teratogenesis

Cardiovascular Research

  • Assessment of cardiac function in mice & rats in     response to a cancer therapeutic agent
  • Introduction of myocardial strain analysis software as an early indicator of cardiotoxicity

 

image description

Shared Resources are core facilities that provide services and access to specialized equipment for research activities.


Rajesh K. Uthamanthil, DVM, PhD, DACLAM

Associate Vice President, Shared Resources