Proteomics Services

Purification, fractionation, and qualitative/quantitative assays of proteins and peptides are performed in the facility by reverse-phase and cation-exchange HPLC. See more
Protein Identification
Proteins are identified through the bottom-up proteomics scheme in which purified proteins or mixtures are digested with a protease and the proteolytic peptides are subjected to tandem mass spectrometry (MS/MS). See more
Protein Modification (PTM) Analysis
Protein modifications that result in mass increases or losses to proteins are readily detectable by mass spectrometry. The facility has extensive experience with characterizing acetylation, methylation, and phosphorylation modifications. See more
Protein Quantification
Techniques such as SILAC, iTRAQ, ICAT, and AQUA are available for quantifying proteins and peptides by mass spectrometry. See more