DLA Typing Services

Location: Thomas Building, D1-315
Contact phone: (206) 667-3369
Contact fax: (206) 667-5978
Contact e-mail: mharkey@fredhutch.org

We amplify, sequence, and identify alleles from several DLA genes in the canine MHC complex.  These DLA alleles must be matched between donor and recipient to facilitate engraftment of transplanted cells, tissues and organs, and to minimize graft versus host disease (GVHD).  They can also play a role in immune-system-related diseases.  Typically, to ensure a reasonable probability of a successful transplant, we type the class I MHC gene, DLA-88 and the class II genes, DRB1, DQA1, and DQB1.  Other DLA genes can also be typed if desired by the user.

For extramural colleagues access to all reagents and SOPs requires execution of a Fred Hutch UBMTA and a nominal fee that covers production and mailing. Please fill out the MTA and email it to mharkey@fredhutch.org. If you need something not listed here, contact us. We may have it.

See our rates.