Filters: Author is Jensen, Michael C [Clear All Filters]
Safety and immunologic effects of IL-15 administration in nonhuman primates.. Blood. 114(12):2417-26.. 2009.
Adoptive transfer of virus-specific and tumor-specific T cell immunity.. Current opinion in immunology. 21(2):224-32.. 2009.
Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates.. The Journal of clinical investigation. 118(1):294-305.. 2008.
Recognition and killing of brain tumor stem-like initiating cells by CD8+ cytolytic T cells.. Cancer research. 69(23):8886-93.. 2009.
A functionalized, injectable hydrogel for localized drug delivery with tunable thermosensitivity: Synthesis and characterization of physical and toxicological properties.. Journal of controlled release : official journal of the Controlled Release Society. 208:76-84.. 2015.
CD19CAR T Cells: From Humble Beginnings to Cancer Immunotherapy's Poster Child.. Cancer journal (Sudbury, Mass.). 20(2):107-11.. 2014.
pEVL: A Linear Plasmid for Generating mRNA IVT Templates With Extended Encoded Poly(A) Sequences.. Molecular therapy. Nucleic acids. 5:e306.. 2016.
High efficiency CRISPR/Cas9-mediated gene editing in primary human T-cells using mutant adenoviral E4orf6/E1b55k "helper" proteins.. Molecular therapy : the journal of the American Society of Gene Therapy.. 2016.
Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells.. Clinical cancer research : an official journal of the American Association for Cancer Research. 19(12):3153-3164.. 2013.
Chimeric γc cytokine receptors confer cytokine independent engraftment of human T lymphocytes.. Molecular immunology. 56(1-2):1-11.. 2013.
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity.. Nature communications. 7:12320.. 2016.
Mathematical modeling of chimeric TCR triggering predicts the magnitude of target lysis and its impairment by TCR downmodulation.. Journal of immunology (Baltimore, Md. : 1950). 184(8):4284-94.. 2010.
Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane.. Journal of immunology (Baltimore, Md. : 1950). 180(10):7028-38.. 2008.
Designing chimeric antigen receptors to effectively and safely target tumors.. Current opinion in immunology. 33:9-15.. 2015.
Design and implementation of adoptive therapy with chimeric antigen receptor-modified T cells.. Immunological reviews. 257(1):127-44.. 2014.
IMMUNOLOGY. Synthetic immunobiology boosts the IQ of T cells.. Science (New York, N.Y.). 350(6260):514-5.. 2015.
Multiplexed gene transfer to a human T-cell line by combining Sleeping Beauty transposon system with methotrexate selection.. Biotechnology and bioengineering.. 2015.
Preclinical Assessment of CD171-Directed CAR T Cell Adoptive Therapy For Childhood Neuroblastoma: CE7 Epitope Target Safety and Product Manufacturing Feasibility.. Clinical cancer research : an official journal of the American Association for Cancer Research.. 2016.
Functional Tuning of CARs Reveals Signaling Threshold above Which CD8+ CTL Antitumor Potency Is Attenuated due to Cell Fas-FasL-Dependent AICD.. Cancer immunology research. 3(4):368-79.. 2015.
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