Facioscapulohumeral muscular dystrophy: consequences of chromatin relaxation.
Publication Type:Journal Article
Source:Current opinion in neurology, Volume 25, Issue 5, p.614-20 (2012)
Keywords:2012, Human Biology Division, September 2012
In recent years, we have seen remarkable progress in our understanding of the disease mechanism underlying facioscapulohumeral muscular dystrophy (FSHD). The purpose of this review is to provide a comprehensive overview of our current understanding of the disease mechanism and to discuss the observations supporting the possibility of a developmental defect in this disorder.
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