Mary Anne Rossing

Appointments and Affiliations

 
 
Fred Hutchinson Cancer Research Center
Division of Public Health Sciences
Full Member
University of Washington
School of Public Health and Community Medicine
Epidemiology
Research Associate Professor
Professional Headshot of Mary Anne Rossing

Mailing Address

Fred Hutchinson Cancer Research Center
1100 Fairview Avenue North
PO Box 19024
M4-C308
Seattle, Washington 98109
United States

Contact

Phone: (206) 667-4630
mrossing@fhcrc.org

Degrees

Ph.D., University of Washington, Epidemiology, 1993.
D.V.M., University of Illinois, Veterinary Medicine, 1980.

Research Interests

The primary focus of my research is the epidemiology of ovarian cancer. I am currently involved in studies of ovarian cancer risk in relation to use of exogenous hormones and other environmental factors. Some of my studies assess the impact of use of ovulation-inducing agents as treatment for female infertility. In other studies, I am examining the role of hormone replacement therapy, and, in particular, the impact of progestins on ovarian cancer risk. Little is known about environmental factors that may influence ovarian cancer risk, although international differences in incidence rates suggest that environmental influences may be involved. In ongoing research, I am examining whether sunlight exposure may influence ovarian cancer risk. My research also explores the interrelation of environmental and hormonal factors with genetic susceptibility to ovarian cancer. The overall goal of my ovarian cancer research is to contribute to a better understanding of pathogenic mechanisms of epithelial ovarian cancer, and to provide information eventually leading to new means of reducing the occurrence of this disease.

Recent Publications

2016
Usset JL, Raghavan R, Tyrer JP, McGuire V, Sieh W, Webb P, Chang-Claude J, Rudolph A, Anton-Culver H, Berchuck A et al..  2016.  Assessment of multifactor gene-environment interactions and ovarian cancer risk: candidate genes, obesity, and hormone-related risk factors.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Abstract
Winham SJ, Pirie A, Chen YA, Larson MC, Fogarty ZC, Earp MA, Anton-Culver H, Bandera EV, Cramer D, Doherty JA et al..  2016.  Investigation of exomic variants associated with overall survival in ovarian cancer.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Abstract
2015
Kar SP, Tyrer JP, Li Q, Lawrenson K, Aben KKH, Anton-Culver H, Antonenkova N, Chenevix-Trench G, Baker H, Bandera E et al..  2015.  Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 24(10):1574-1584. Abstract
Pearce CL, Stram DO, Ness RB, Stram DA, Roman LD, Templeman C, Lee AW, Menon U, Fasching PA, McAlpine JN et al..  2015.  Population distribution of lifetime risk of ovarian cancer in the United States.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 24(4):671-6. Abstract
2014
Block MS, Charbonneau B, Vierkant RA, Fogarty Z, Bamlet WR, Pharoah PDP, Chenevix-Trench G, Rossing MA, Cramer D, Pearce CL et al..  2014.  Variation in NF-κB Signaling Pathways and Survival in Invasive Epithelial Ovarian Cancer.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. Abstract
2013