Polly A. Newcomb
Postdoctoral Fellow, University of Wisconsin-Madison, Cancer Biology, 1986.
Ph.D., University of Washington, Epidemiology.
M.P.H., University of Washington, Epidemiology.
As a cancer epidemiologist, the focus of my research is on the identification of modifiable risk factors for common cancers, particularly breast and colon cancer. Since many of these risk factors appear to have only modest magnitudes of effect, more precisely identifying susceptible individuals defined by genes, epigenetic changes, or personal characteristics such as body size may help direct investigations in the population, laboratory and clinic. These risk factors are also plausibly related to survival after diagnosis and several studies are examining characteristics associated with longevity.
Other interests include: the interaction of genes and the etiology of cancer; and approaches to the secondary prevention of cancer using new markers for early detection, as well as established technologies.
American Association for Cancer Research
American Society of Preventive Oncology
Society for Epidemiologic Research
The International Society for Research in Human Milk and Lactation
Honors and Awards
2009, UICC Yamagiwa-Yoshida Memoria International Cancer Study Fellowship Award, UICC
2009, Mid-Career Women Faculty Professional Development Seminar, AAMC
2009, Peggy Means Leadership Development Award, FHCRC
2010, University of Washington School of Public Health Faculty Mentor Award, University of Washington, Seattle
2002-2003, Acting Program Head, Fred Hutchinson Cancer Research Center, Cancer Prevention, Public Health Sciences
1996-1998, Associate Professor (Affiliate), University of Washington, Public Health, Epidemiology
1995-1997, Associate Member, Fred Hutchinson Cancer Research Center
1995-1999, Associate Professor, University of Wisconsin-Madison, School of Medicine and Public Health, Medicine
1994-1995, Associate Professor, University of Wisconsin-Madison, School of Medicine and Public Health, Human Oncology
1988-1994, Assistant Professor, University of Wisconsin-Madison, School of Medicine and Public Health, Human Oncology
1987-1988, Assistant Scientist, University of Wisconsin-Madison, School of Medicine and Public Health, Human Oncology
1987-1988, Assistant Scientist, University of Wisconsin-Madison, School of Medicine and Public Health, Preventive Medicine
The History of a Name: The American Society for Preventive Oncology Renames Its Highest Honor the Joseph F. Fraumeni, Jr., Distinguished Achievement Award.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 26(3):431-432.. 2017.
Health-related behaviors and mortality outcomes in women diagnosed with ductal carcinoma in situ.. Journal of cancer survivorship : research and practice.. 2017.
Urinary Cadmium and Mammographic Density.. Epidemiology (Cambridge, Mass.). 28(1):e6-e7.. 2017.
Reproductive factors and risk of colorectal polyps in a colonoscopy-based study in western Washington State.. Cancer causes & control : CCC.. 2017.
Germline miRNA DNA Variants and the Risk of Colorectal Cancer by Subtype.. Genes, chromosomes & cancer.. 2016.
Cross-cancer genome-wide analysis of lung, ovary, breast, prostate and colorectal cancer reveals novel pleiotropic associations.. Cancer research. 76(17):5103-5114.. 2016.
Relationship of prediagnostic body mass index with survival after colorectal cancer: Stage-specific associations.. International journal of cancer. 139(5):1065-72.. 2016.
Reliability of plasma lipopolysaccharide-binding protein (LBP) from repeated measures in healthy adults.. Cancer causes & control : CCC. 27(9):1163-1166.. 2016.
Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.. 2016.
Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer.. Cancer epidemiology. 44:1-4.. 2016.
Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer.. PLoS genetics. 12(10):e1006296.. 2016.
Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH.. International journal of cancer. 139(7):1557-1563.. 2016.
Alcohol Consumption and the Risk of Colorectal Cancer in Mismatch Repair Gene Mutation Carriers.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.. 2016.
Urinary heavy metals in Hispanics 40-85 years old in Doña Ana County, New Mexico.. Archives of environmental & occupational health. 71(6):338-346.. 2016.
Urinary Cadmium and Risk of Invasive Breast Cancer in the Women's Health Initiative.. American journal of epidemiology. 183(9):815-23.. 2016.
Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer.. British journal of cancer.. 2016.
Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome.. International journal of epidemiology. 45(3):940-953.. 2016.
Cigarette Smoking Before and After Breast Cancer Diagnosis: Mortality From Breast Cancer and Smoking-Related Diseases.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2016.
Racial Patterns of Peripheral T-Cell Lymphoma Incidence and Survival in the United States.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2016.
CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk.. British journal of cancer. 114(2):221-9.. 2016.
Common Genetic Variation and Survival after Colorectal Cancer Diagnosis: A Genome-Wide Analysis.. Carcinogenesis. 37(1):87-95.. 2016.
PMS2 monoallelic mutation carriers: the known unknown.. Genetics in medicine : official journal of the American College of Medical Genetics. 18(1):13-19.. 2016.