David H. Myerson
M.D., Einstein College of Medicine, 1979.
Ph.D., Einstein College of Medicine, 1979.
Sc.B. (Magna cum laude), Brown University, 1970.
I have been pursuing the detection of viruses by molecular methods, including CMV and HCV in the past. At present I am working on the detection of HHV-6 as a potential etiology for an encephalopathy syndrome post-transplant. I am interested in the detection of viruses and other infectious diseases in routinely fixed, formalin-fixed, paraffin-embedded tissue sections and also developed in situ hybridization procedures for this purpose. With the possibility that hematopoietic transplants may give rise to non-hematopoietic tissue, post-transplant tissue is being investigated for donor cells by either combined immunohistochemistry-in situ hybridization or double in situ hybridization. In addition, I have a clinically-related research interest in the diagnosis and categorization of myelodysplastic syndromes and myeloproliferative disorders. Collaborations include work with CMV (Dr. Boeckh), HCV (Dr. McDonald), non-host cells (Dr. Nelson), and myelodysplasia (Dr. Deeg).
1979 - 1982 Resident in Anatomic Pathology, Department of Pathology, College of Physicians and Surgeons, Columbia Presbyterian Medical Center, New York, New York.
9/81 - 12/81 Visiting Fellow, Virology Laboratory, Veterans Administration Medical Center, Yale University School of Medicine, West Haven, Connecticut. (Advisor: Dr. G.D. Hsiung).
12/81 - 12/83 Fellow, Tumor Biology Program, Fred Hutchinson Cancer Research Center, Seattle, Washington. (Advisor: Dr. J.K. McDougall).
1/84 - 9/86 Associate in Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington.
7/85 - 2/87 Courtesy Member, Swedish Hospital Medical Center, Seattle, Washington.
11/85 to 6/91 Assistant Professor, Department of Pathology, University of Washington, Seattle, Washington.
9/86 to 6/92 Assistant Member, Clinical Research, FHCRC, Seattle, Washington.
9/91 to 12/00 Co-director of the HCV Laboratory, FHCRC.
2/87 to date Active Staff, Swedish Hospital Medical Center, Seattle, Washington.
3/88 to date Graduate Faculty, University of Washington, Seattle, Washington.
10/89 to date Co-director of the Molecular Cytogenetics Laboratory, FHCRC
7/91 to date Associate Professor, Department of Pathology, University of Washington, Seattle, Washington.
7/92 to date Associate Member, Clinical Research, FHCRC.
Prevalence of chromosomally integrated human herpesvirus 6 in patients with human herpesvirus 6-central nervous system dysfunction.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 21(2):371-3.. 2015.
NIH Consensus development project on criteria for clinical trials in chronic graft-versus-host disease: II. The 2014 Pathology Working Group Report.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 21(4):589-603.. 2015.
Keratinocyte Dysplasia in Hematopoietic Stem Cell Transplantation Recipients in the Day-28-to-84 Posttransplantation Period.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 18(8):1281-6.. 2012.
Secondary pulmonary alveolar proteinosis: a confusing and potentially serious complication of hematologic malignancy.. Journal of thoracic imaging. 24(2):115-8.. 2009.
Renal thrombotic microangiopathy after hematopoietic cell transplant: role of GVHD in pathogenesis.. Clinical journal of the American Society of Nephrology : CJASN. 4(2):345-53.. 2009.