Ph.D., Stanford University, Statistics, 1967.
B.A., Reed College, Mathematics, 1962.
Statistical methods in epidemiology.
Childhood cancer, especially Wilms tumor.
During 1969-2002 I served as statistician to the National Wilms Tumor Study Group whose Data and Statistical Center I direct at the FHCRC. I continue as PI on a longitudinal study of the survivors.
Continued follow-up and analysis of the large Wilms tumor cohort to ascertain rates of second malignant neoplasms, renal failure, cardiomyopathy and adverse pregnancy outcome.
Methods for design and statistical analysis of epidemiological studies involving complex, outcome dependent sampling
(Reading, Writing, Speaking)
French: (Functional, Basic, Functional)
Spanish: (Functional, Basic, Basic)
American Association for the Advancement of Science
American Association of University Professors
American Statistical Association
Institute of Medicine
International Biometric Society
International Statistical Institute
Royal Statistical Society
Society for Epidemiologic Research
Honors and Awards
2006, Honorary Life Member, International Biometric Society
2002, Nathan Mantel Award, American Statistical Association (Biometrics Section)
2001, Docteur Honoris Causa, Universite Victor Segalen Bordeaux II
1995, Snedecor Award, Committee of Presidents of Statistical Societies
1995, R.A. Fisher Award and Lecture, Committee of Presidents of Statistical Societies
1994, Honorary Fellow, Royal Statistical Society
1984, Fellow, American Association for the Advancement of Science (AAAS)
1982-1983, Senior US Scientist Award (Sonderpreis), Alexander von Humboldt Foundation
1978, Spiegelman Gold Medal Award, American Public Health Association
1976, Fellow, American Statistical Association
Reply to Wilms tumor and breast cancer.. Cancer. 121(12):2099-100.. 2015.
Z-estimation and stratified samples: application to survival models.. Lifetime data analysis.. 2015.
Non-HLA type 1 diabetes genes modulate disease risk together with HLA-DQ and islet autoantibodies.. Genes and immunity. 16(8):541-551.. 2015.
Outcome of patients with stage II/favorable histology wilms tumor with and without local tumor spill: A report from the National Wilms Tumor Study Group.. Pediatric blood & cancer. 61(1):134-9.. 2014.
Pulmonary disease after treatment for wilms tumor: A report from the national wilms tumor long-term follow-up study.. Pediatric blood & cancer. 60(10):1721-6.. 2013.
Using the Whole Cohort in the Analysis of Case-Control Data: Application to the Women's Health Initiative.. Statistics in biosciences. 5(2). 2013.
Clinicopathologic Findings Predictive of Relapse in Children With Stage III Favorable-Histology Wilms Tumor.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology.. 2013.
Treatments and outcomes for end-stage renal disease following Wilms tumor.. Pediatric nephrology (Berlin, Germany).. 2012.
Islet autoantibodies and residual beta cell function in type 1 diabetes children followed for 3-6 years.. Diabetes research and clinical practice.. 2012.
Risk factors for end stage renal disease in non-WT1-syndromic Wilms tumor.. The Journal of urology. 186(2):378-86.. 2011.
Portal hypertension in children with Wilms' tumor: a report from the National Wilms' Tumor Study Group.. International journal of radiation oncology, biology, physics. 77(1):210-6.. 2010.
Long-term outcomes for infants with very low risk Wilms tumor treated with surgery alone in National Wilms Tumor Study-5.. Annals of surgery. 251(3):555-8.. 2010.
Pregnancy outcome after treatment for Wilms tumor: a report from the national Wilms tumor long-term follow-up study.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 28(17):2824-30.. 2010.
Secondary malignant neoplasms after Wilms tumor: an international collaborative study.. International journal of cancer. Journal international du cancer. 127(3):657-66.. 2010.
Renal failure does not preclude cure in children receiving chemotherapy for Wilms tumor: a report from the National Wilms Tumor Study Group.. Pediatric blood & cancer. 50(2):242-5.. 2008.
Treatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A report from the National Wilms Tumor Study Group.. Pediatric blood & cancer. 50(2):236-41.. 2008.
Obstetric history and birth characteristics and Wilms tumor: a report from the Children's Oncology Group.. Cancer causes & control : CCC. 19(10):1103-10.. 2008.